Testosterone and Heart Disease

low_testosterone_heart_disease_baucom_instituteFor years, we’ve known that low testosterone for men has created many issues but now there is evidence that it is linked to heart disease. Here are a few of the findings (JAMA, Aging Male, Geriatrics, European Heart Journal,Circulation, JACC, JCEM, Endocrinology):

Low Testosterone and Heart Disease

  • Men with coronary heart disease had significantly lower total testosterone.
  • A study showed a correlation between lower testosterone levels and conditions associated with cardiovascular disease.
  • Another study showed that men with coronary heart disease had significantly lower levels than the control group.
  • Low testosterone levels have been shown to be associated with atherosclerosis in men.

High Estrogens and Heart DiseaseHEART-DISEASE-low testosterone-baucom-institute

  • A study showed that elevated circulating estradiol is a predictor of progression of carotid artery issues.
  • High estradiol levels in men were associated with acute myocardial infarctions.
  • Elevated levels of estrogen in men are associated with an increased risk of heart disease.

Testosterone Replacement and Heart Disease

  • A study showed that with an increase of testosterone there was a 14% drop in risk of death.
  • A study revealed that testosterone replacement was associated with a decrease in HDL-C and lipoprotein a.
  • Introduction of testosterone increases coronary artery blood flow in men with coronary heart disease.
  • Testosterone replacement has shown to decrease inflammation and lower total cholesterol.

Do you know a male in his 40′s or older with a history of heart disease in his family? Share these studies and encourage him to seek medical attention, particularly a doctor educated on the connection of hormones and disease prevention.

If you are a medical professional, what are your findings on the connection of low testosterone and heart disease?

What Does Gluten Do?

Rose Family Fall 2013 074Maddy’s story begins like so many others – born into a middle class family in the midwest, she has had the privileges of most teenagers her age and is now a freshman Criminal Justice major at Olivet Nazarene University in Bourbonnais, Illinois.

Maddy has found that eating is a rather difficult thing, especially at college, even though they have a gluten-free menu, because of all the temptations on the regular menu. She has a gluten intolerance, on the extreme end. It makes it hard to take care of herself away from home, yet she’s working hard to do it, realizing that eating gluten is just not worth the pain.

Maddy says, “First off, you can tell as you are eating it you start to feel full but you aren’t sure if you are bloated or if you are actually getting full. After you’ve eaten, about only 30 minutes later, you start to get indigestion. You get really bad issues that come with extreme gastrointestinal stress, extreme nausea, heavy fatigue, you become moody and irritable and it can even result in vomiting. You also have energy depletion and headaches that include throbbing, making it hard to focus. Speaking of focus, your attention span is decreased, making it hard to work, study, pay attention in class, and go through daily activities that would normally not be an issue for you. You also feel heavy, muggy, miserable, and all around sickly. I also get hot and cold flashes sometimes – that’s when I know it’s really severe. It wasn’t until I talked to Dr. Baucom about my symptoms that I realized why I was having trouble every time I ate. She had me read various articles on gluten, making me realize I was on the extreme end of this issue.”

What is gluten? It is a protein that has been engineered as a component of wheat that provides the elastic qualities for baked goods. But the protein is also difficult to digest. And even a healthy intestine does not completely break gluten down. For those with celiac disease, the undigested gluten essentially causes the body’s immune system to lash out at itself, leading to malabsorption, bloating and diarrhea — the classic gastrointestinal symptoms — but also, at times, joint pain, skin rashes, etc.

Joseph A. Murray, a gastroenterologist at the Mayo Clinic in Rochester, Minnesota says of gluten-intolerance, “It truly has become more common.” Comparing blood samples from the 1950s to the 1990s, Murray found that young people today are nearly five times as likely to have celiac disease, for reasons he and others researchers cannot explain. And it’s on the rise not only in the U.S. but also in other places where the disease was once considered rare, like Mexico and India. “We don’t know where it’s going to end,” Murray says.

Mark Hyman, M.D. practicing physician and founder of The UltraWellness Center is a pioneer in functional medicine. He’s done some extensive study on the effects of gluten. He says that a review paper in The New England Journal of Medicine listed 55 “diseases” that can be caused by eating gluten. (iv) These include osteoporosis, irritable bowel disease, inflammatory bowel disease, anemia, cancer, fatigue, canker sores, (v) and rheumatoid arthritis, lupus, multiple sclerosis, and almost all other autoimmune diseases. Gluten is also linked to many psychiatric (vi) and neurological diseases, including anxiety, depression, (vii) schizophrenia, (viii) dementia, (ix) migraines, epilepsy, and neuropathy (nerve damage). (x) It has also been linked to autism.(ix)

Gluten sensitivity is actually an autoimmune disease that creates inflammation throughoutgluten-warning-baucom-institute the body, with wide-ranging effects across all organ systems including your brain, heart, joints, digestive tract, and more. It can be the single cause behind many different “diseases.” To correct these diseases, you need to treat the cause–which is often gluten sensitivity–not just the symptoms.

How can you know if you are gluten-intolerant? Try going off food that causes the symptoms – breads, pastas, sauces made with flour, chips, french fries, chocolate, anything with wheat or barley in it, etc. Even body and hair care products can have gluten and can be absorbed through the skin. See how you feel. If you have less symptoms like intestinal distress, bloating, etc. you know that gluten was at least a culprit. Most importantly seek a medical professional educated in restorative medicine or naturopathic education. Unfortunately, most MD’s are not aware nor educated on the effects of gluten, although society’s awareness is pushing the medical community to become more aware.

How do you relate to Maddy’s story? What symptoms cause you to think you may be gluten intolerant?

To Age or Not To Age

Do we actually have a choice whether we age or not? Can we restore our bodies to health or is all the talk about longevity and restorative medicine just a bunch of hype?

Most people are interested in knowing how to lengthen their life span and create a healthier, happier life at the same time. But the average person deals mostly in putting out fires when symptoms occur, going to the doctor and getting some medicine to deal with the ailment, having surgery, etc.

restorative_medicine_baucom_instituteWhat if we got in front of the ol’ “8 ball”, so to speak, and became not only a “preventative health” society but a restorative one? Think of the disease prevention and quality of life we would create for ourselves!

There are now doctors becoming more interested in this type of medicine. In fact, more organizations of doctors that believe in not only holistic medicine but in restorative medicine are becoming more prevalent. There are also organizations in which MD’s, ND’s, NMD’s, and DO’s are sitting in the same conferences and are collaborating on the idea of restorative medicine.

Disease is rampant and there doesn’t seem be any better answer in dealing with these diseases other than drug therapies, surgery and living out one’s life. Not any kind of quality of life at all.

No wonder doctors are turning to other answers.

According to AARM (Association for the Advancement of Restorative Medicine), “. . . the principle is to actually restore fundamental balance and not simply suppress, palliate, or otherwise superficially treat symptoms. Many endocrine disorders and chronic diseases have a limited possibility to be overcome by conventional approaches.  Restorative Medicine offers new scientific data that leads us not to conform or succumb but rather spearheading the rebirth of restorative health.”

“Chronic diseases have now eclipsed infectious diseases, and the old paradigm of focusing on cures is not working,” according to Harvard Medical student, Sandeep Kishore. He says instead of focusing on medications to treat disease, we should focus on causes and not just treat symptoms.

Dr. Michael Friedman, President of AARM, says “the goal [of restorative medicine] is to repair tissue degeneration, optimize cellular and metabolic function, and build organ health. In many cases, medications can be discontinued altogether over time as health and vitality are truly restored.”

What do you think about approaching health from a more restorative perspective?

The X Factor

the-x-factor-metabolic-syndrome-baucominstitute

We’re always looking for the next big thing but the next big thing is already here – Metabolic Syndrome X – the biggest problem in America! The USA has the highest percentage of obese in the world, 34% female and 27.7% male, 35% of whom are Mexicans and 40% African American males.

What is Metabolic Syndrome X? In our blog last week, we shared that this syndrome is a result of having three or more metabolic risk factors: insulin resistance, elevated blood pressure, abdominal obesity, high lipids – TG, LDL, etc.

“94% of the rats who were allowed to choose between sugar and cocaine, chose sugar. Even rats who were addicted to cocaine switched their preference to sugar!”

Here are the symptoms:

  • Borderline high or normal blood glucose
  • High triglycerides (above 2.3 mmol/l)
  • Low HDL (good cholesterol)
  • High blood pressure
  • Hypoglycemia
  • Excess weight resistant to dieting
  • Skin tags
  • Osteoarthritis

According to researchers at Yale University School of Medicine, insulin resistance in skeletal muscle leads to changes in energy storage and insulin-resistant individuals rerouted carbohydrates to liver fat production. This leads to elevated triglycerides in the blood by as much as 60% while lowering HDL (good) cholesterol by 20%. In a study done by Yale, participants who were young and lean, with no excess abdominal fat became insulin resistant. The good news is, they found that insulin resistance in skeletal muscle can be treated with one simple method – exercise!

Let’s talk about sugar for a moment, because that it ultimately the biggest culprit in the cause of The X Factor.

The average American eats 142 pounds of sugar a year, or about 2.5 pounds each week, a 23% increase over the last 25 years! And most of it is coming from, one guess . . . soft drinks – which includes artificially sweetened drinks as well! In the US, ¼ or 22% of the daily calories are from drinks, according to a report called “What America Drinks.”

According to Drs. Fischer, Hommel, Fiedler, and Bibergeil, in a study done on “reflex mechanism on insulin secretion,”  we are seeing that soft drinks are linked to Metabolic Syndrome:

  • Men and women who drank more than one soda daily had a 48% adjusted higher prevalence
  • insulin level rises in the first minute after the start of a carbohydrate-rich meal, vs glucose level rising in the third minute of a balanced diet
  • An increase in triglyceride levels and LDL
  • Consumption rose 135% of high fructose corn syrup between 1977 and 2001
  • Americans eat an average of 132 calories of high fructose corn syrup a day

In a lab experiment with rats by the University of Bordeaux called “Intense Sweetness Surpasses Cocaine Reward,” 94% of the rats who were allowed to choose between sugar and cocaine, chose sugar. Even rats who were addicted to cocaine switched their preference to sugar!

Obviously, we have to get over our addiction to this satiable substance! In the meantime, many changes have to take place to get this X Factor under control.

Doctors, in weight-loss fields, GP’s, restorative, and otherwise, are all finding that to get this syndrome under control several factors have to take place:

  • Balance glucose/insulin levels
  • Increase metabolism
  • Increase fat burning
  • Create appetite suppression

A study done by Sweden’s Karolinska Institute European Association for the Study of Diabetes found that a natural substance can greatly help in this fight:  Green Tea Catechins or EGCG (epigallocatechin gallate). After 5 and 10 weeks of treatment with EGCG, and GlaxoSmithKline’s diabetes drug Avandia, the blood sugar and insulin levels of mice were tested. The researchers found that the mice did just as well on the green tea extract as they did on the drug. The extract has been found to have these benefits:

  • Reduces fat absorption
  • Reduces LDL cholesterol/TG levels
  • Reduces glucose/insulin levels
  • Increases beta oxidation
  • Helps decrease appetite

Which ultimately:

  1. Reduce body weight gain
  2. Reduce body fat accumulation
  3. Stimulate oxidation in the liver

All in all, here are the recommendations by Alexander McLellan, ND, Neuropathic Physician in Halifax, Nova Scotia, and professor at the Canadian School of natural Nutrition and Chief Medical Officer for three clinical research trials in Diabetic Neuropathy in Canada and the US, in treating obesity and Metabolic Syndrome: Check thyroid function, Restrict carbs, Check for food allergies, Keep hydrated, Get stress levels down, Get to a support group and stay educated, Detox, detox, detox! The bottom line? It’s the samo, samo:

  • Eat right
  • Exercise more
  • Don’t rely on a “magic pill”

What do you think?

BIG Bellies – drugs or lifestyle change?

belly_fat_diabetes_baucominstituteWe have a major problem in our society . . . we’re fat! Especially in the belly. Why? Are some of us presupposed by our DNA to struggle with weight? Are we just lazy? Is it all because of what we eat?

Let’s break it down.

  • There are an estimated 23.6 million people in this country with diabetes.
  • There are another 57 million with high blood sugars
  • Between 2000 and 2010, the prevalence of a BMI >40 kg m(-2) (type III obesity), calculated from self-reported height and weight, increased by 70%
  • Approximately 17% (or 12.5 million) of children and adolescents aged 2—19 years are obese. (CDC)
  • Since 1980, obesity prevalence among children and adolescents has almost tripled.

It all comes down to insulin resistance.

What does insulin do? It helps the body utilize glucose – it’s really the key that unlocks the cell door so glucose can pass into it from the bloodstream. Once inside the cell, glucose is used either for energy or stored for use later in the form of glycogen in the liver and muscles. belly_fat_metabolic_syndrome_baucominstitute

Insulin resistance occurs when a normal amount of insulin is not able to open that cell door so the body secretes even more insulin in an attempt to maintain normal blood glucose levels or when there aren’t enough insulin receptors (the average overweight person has 75% less receptors).

So, glucose stays in the bloodstream which is sent to the liver and then converted into fat and then stored throughout the body. These fat cells are even more insulin resistant and often coalesce near the middle – a lot of belly fat. Other symptoms are: headache, day-time drowsiness, insomnia, fatigue,  frequent illnesses, sugar cravings, erratic and insatiable appetite.

And then there’s Metabolic Syndrome – Syndrome X a result of having three or more metabolic risk factors: insulin resistance, elevated blood pressure, abdominal obesity, high lipids – TG, LDL, etc.

What’s the treatment? Do we treat the problem with drugs or with lifestyle changes?

3200 adults with impaired blood sugar control were put into three groups:

  • Metformin (drug)
  • Exercise 150 minutes per week (lifestyle)
  • Usual Care

After three years, there was a reduction in progression to diabetes:

  • 58% in lifestyle group
  • 31% in drug group

In 2008:

  • two clinical trials revealed that diabetic patients on antidiabetic medications gained no significant protection from heart attack and stroke
  • a third study was ended when interim results showed more deaths in volunteers using diabetes drugs for intensive blood sugar control.

So what’s the answer? Lifestyle change – the right nutrition and exercise. It’s simple. Age old. Cliche. But it works. We just don’t want to have to change.

Nutrition -

  • 30% protein with high fiber and avoidance of starch, sugary carbs
  • abundant greens and fresh vegetables
  • frequent ginger, garlic, curcumin, oregano, onions
  • avoidance of refined processed foods like pasta and bread
  • Avoidance of artificial sweeteners and sugars
  • Intake of nuts, legumes and lentils

Supplements -

  • Herbal treatments – Fenugreek, Guar Gum, apple pectin, beet powder, oat fiber, etc.
  • Niacin
  • Lecithin
  • Vitamin E
  • Nattokinase
  • Fish oil
  • magnesium
  • Green Tea, etc.

A restorative or naturopathic physician should always be consulted when creating a pathway to change when dealing with insulin resistance and metabolic syndrome.

What are your thoughts on treatment insulin resistance leading to metabolic syndrome?

New Year, New You!

happy_healthy_restored_people_baucominstitute

It’s the new year! It’s 2014. A fresh start. A new beginning. At ANY age!

Can we actually reverse the aging process and restore our bodies to health or is all the talk about longevity and restorative medicine just a bunch of hype?

Most people are interested in knowing how to lengthen their life span and create a healthier, happier life at the same time. But the average person deals mostly in putting out fires like when symptoms arrive, going to the doctor and getting some medicine to deal with the ailment.

What if we got in front of the ol’ “8 ball”, so to speak, and became not only a “preventative health” society but a restorative one? Think of the disease prevention we would create in our world and the quality of life we would create!

There are now doctors becoming more interested in this type of medicine. In fact, there are more organizations of doctors that believe in not only holistic medicine but in restorative medicine which are becoming more prevalent. There are also organizations in which MD’s, ND’s, NMD’s, and DO’s are sitting in the same conferences and are collaborating on the idea of restorative medicine.

Disease is rampant and there doesn’t seem be any better answer in dealing with these diseases other than drug therapies, surgery and living out one’s life with the disease. Not any kind of quality of life at all.

No wonder doctors are turning to other answers.

According to AARM (Association for the Advancement of Restorative Medicine) says, “. . . the principle is to actually restore fundamental balance and not simply suppress, palliate, or otherwise superficially treat symptoms. Many endocrine disorders and chronic diseases have a limited possibility to be overcome by conventional approaches.  Restorative Medicine offers new scientific data that leads us not to conform or succumb but rather spearheading the rebirth of restorative health.”

“Chronic diseases have now eclipsed infectious diseases, and the old paradigm of focusing on cures is not working,” according to Harvard Medical student, Sandeep Kishore. He says instead of focusing on medications to treat disease, we should focus on causes and not just treat symptoms.

Dr. Michael Friedman, President of AARM, says “the goal [of restorative medicine] is to repair tissue degeneration, optimize cellular and metabolic function, and build organ health. In many cases, medications can be discontinued altogether over time as health and vitality are truly restored.”

What do you think about approaching your health from a more restorative perspective?

There’s a “Pause” for Men Too!

Male-Andropause-BaucomInstitute

Male Andropause. You may have never heard of it, especially if you are a woman under 30. However, it is a very real and prevalent issue for men, especially after age 40. Let’s start with what it is and then what to do about it.

To put it simply, andropause is the steady decline in the hormone testosterone. It usually effects men around the age of 40 and continues for a longer period of time, possibly lasting for decades, than menopause with women which can have more extremeandropause_graph effects but over a shorter period of time. Most men think these symptoms are just a part of aging and that they should just accept their fate. They couldn’t be more wrong. In fact, by age 45-55 men can experience the same types of effects similar to menopause.

The effects can include changes in attitude and mood, mild depression, fatigue, lower sex drive, reduced erections, weight gain in the middle, loss of energy, and reduction in physical agility because of the loss of muscle mass.

So what’s the answer? It seems inevitable. It stands to reason that if the loss of testosterone is the cause then the replacing of testosterone would be the answer. True, but how do you replace an organic chemical that the body itself reproduces? This is where the answer and the problem both lie, as if two sides to the same coin.

Hormone therapy has become more common in treating the effects of menopause in women. However, the side-effects have become too dangerous, like when men take Viagra to enhance their sexual performance. It is not a natural component; therefore the body cannot assimilate it without side effects.

Bio-identical hormones have become preferable due to their natural effects on the body. These same types of bio-identical, natural hormones are now available to men as well. The bio-available testosterone not only increases muscle mass and improves a guy’s general well-being, it also lowers cholesterol, enhances libido and sexual energy, and helps prevent pre-mature heart disease.

If you have these symptoms from aging, even if you are just in your 40’s, don’t wait until they are worse. Contact us today at The Baucom Institute to learn from your own “Age Management Plan” what you need at your age.

What are some symptoms you have noticed in yourself or someone else you care about? We would love to hear from you.

Am I Losing It or Does Anybody Feel This Way?

Portrait of a middle aged woman sitting in a chair and looking sad

Hormones are vital in protecting and telling the body what to do. An important part of age management medicine is measuring and, where necessary, supplementing important hormones that decline, but contribute to longevity. Often patients come to the Baucom Institute with complaints of fatigue, decreased libido, poor concentration, and weight gain despite proper exercise and nutrition. The missing piece to their puzzle is often hormonal restoration and balance. When we restore and balance hormones to their youthful level, we use bio-available hormones. These bio-available hormonal messengers are the same as our bodies produce and can be utilized as natural restorative factors to qualify aging. Hormone restoration and balancing requires precise testing and monitoring. It should only be performed under the medical management of a qualified physician.

COMPARING HERBS AND BIO-AVAILABLE HORMONES

Bio-available hormones require a prescription by a physician. Often people confuse the difference between bio-available hormones and herbs that stimulate hormones. Herbs, or holistic naturopathic medicine, can be a contributor to the wholeness of a being, but instead of using naturopathic herbs to simulate what these hormones can do, as physicians we can have these hormones compounded by a pharmacy. In today’s world of medicine, many pharmaceutical companies are also now beginning to produce bio-available hormones.

A PERSONALIZED HORMONE BALANCING AND RESTORATION PLAN

Hormones work in concert with one another. The vital glands that send these important messengers throughout our brain and the rest of our body do so in a synchronized balanced manner. It’s our job, at the Baucom Institute, to identify if hormone balancing and restoration is appropriate and, if so, format for that patient a hormonal balancing and restoration plan designed to achieve increased vitality and youthful exuberance.

Learn More about Bio-Available Hormones

What symptoms do you struggle with?

Nutrition – Convenient Yet Effective

1364832703339We’ve been talking the last month about the bacteria, fungi, yeast, etc. that can build up in the gut and how to treat the issues that occur as a result. One of the overarching ways to take care of the gut is nutrition. There isn’t anything more convenient and effective on the market today than Juice Plus+. It is a complete vegetable and fruit supplement in a capsule. It is the actual vegetables and fruits themselves, so the body can process the nutrition just as if you were eating that many foods.

Clinical research has showcased the benefits of adding Juice Plus+ to your diet and it’s those studies that impressed Dr. Baucom of The Baucom Institute to take a closer look at the product and eventually start herself, her family and her patients on it.

The Juice Plus+ Clinical Research that is published in medical and scientific journals can be accessed via pubmed.gov.

stellar-events-pic-juice-plus

Pubmed is part of the National Library of Medicine of the National Institutes of Health (NIH) . It is one of the most reputable resources for obtaining peer reviewed journals articles.

There are over 20 gold standard studies that have been conducted in leading hospitals and universities around the world.

Because of this substantial evidence, Juice Plus+ stands above the rest in nutrition effectiveness.

How do you supplement your diet? If you are a doctor or nutritionist, what do you use to enhance your patients’ nutrition?

Intestinal Health – the Four “R” Program: Part IV – Obesity

mid section view of a man sitting on a bench in a park

In Part I of our four-part series, we looked at the gut and how bacteria plays a part in a good way and a bad one as well as the treatment for it – the Four R Program - four steps to creating a healthy gut:  Remove, Replace, Reinoculate, Repair.

In Part II, we looked at bacteria specifically in relation to our gut health and what it does to create havoc in our system, not just our gut.

In Part III, we dealt with yeast and fungi in relation to the gut and the treatment options that are available to deal with these two gut busters.

In Part IV, we’ll look at how obesity plays a part in overall gut health.

Why?

Research has found that obesity has a microbial component that alters caloric yield from ingested food. Altering the gut microbiota may also improve insulin sensitivity and glucose intolerance.

What causes this?

Bacteria (Firmicutes and Bacteroidetes classes – Clostridiasp., Streptomyces sp., Lactobacillus sp., Mycolplasma sp., Bacillus sp., Bacteroides sp., and Prevotella sp.) known to increase caloric extraction from food are present. Basically, one thing leads to another – bacteria takes away what the body needs, coupled with a Western diet and lack of exercise, which leads to inflammation, leading to affects on the body i.e. diabetes, cancers, etc.

Jeff Leach with the Human Food Project states in his article Anthropology of Microbes, “In chatting with the researchers from Shanghai (about a 26 year old man at 300+ pounds who lost weight with a low-fat, high carb diet and found to have elevated levels of Enterobacter cloacae subsp. or B9), it’s clear that our B29 microbe is not the only heavy-duty endotoxin-producing bacteria that is contributing to obesity and associated metabolic disorders in mice and humans. Several members within the larger Enterobactereriaceae family (within the phylum Proteobacteria) will emerge as opportunistic pathogens as well. Opportunistic in that they only cause significant damage to the host under elevated conditions which are brought on by a western diet and lifestyle (apparently). . . .therefore, ipso facto, elevated levels of Enterobacter cloacae subsp. (B29) in your gut in the presence of a high fat diet maycause an increase in your circulating levels of LPS endotoxins which will in turn increase your levels of inflammation which will definitely contribute to a cascade of metabolic disorders including, but not likely limited to, obesity and type 2 diabetes.” (http://humanfoodproject.com/are-you-carrying-the-obesity-pathogen/)

What are the treatment options?obesity_SS_131375909_081613-617x416

In order to alter the gut for microbiota:

  1. balance of predominant bacteria using the 4R protocol (below)
  2. remove opportunistic bacteria, especially Bacillus sp.
  3. supplement with Bifidobacter sp., and S. boulardii
  4. reduce refined carbohydrates
  5. address all the GI imbalances.

In case you forgot the the 4 R’s to intestinal health, they are:

1. Remove – offending foods, medications, gluten and reduce poor quality fats, carbohydrates, sugars and fermented foods.

2. Replace – what is needed for normal digestion and absorption i.e. betaine HCI, pancreatic enzymes, herbs to aid in digestion (licorice, marshmallow root), fiber and water.

3. Reinoculate – with favorable microbes (probiotics i.e. Lactobacillus sp.) and supplement with prebiotics (i.e. inulin, beta glucan and fiber).

4. Repair – mucosal lining by giving support to healthy intestinal mucosal cells, goblet cells and to the immune system i.e. L-glutamine, zinc, vitamin C.

What are your thoughts concerning obesity and the effect it has on gut health?